2E
2E or II-E may refer to:
2nd meridian east, a longitude coordinate
Apple IIe, a 1983 model in the Apple II series of personal computers
Aptera 2e, the 2009 and first model in the Aptera 2 Series by Aptera Motors
Oflag II-E, a prisoner of war camp in Germany
2nd arrondissement of Paris
Transcription Factor II E
Twice exceptional, an individual with special needs who is also gifted.
A reference to data collected by the Einstein Observatory (version 2)
YoRHa No. 2 Type E, the actual designation of YoRHa No. 2 Type B in Nier: Automata
Advanced Dungeons & Dragons 2nd Edition, a version of the Dungeons & Dragons role-playing game that debuted in 1989.
Pathfinder Second Edition, a version of the Pathfinder role playing game that debuted in 2019.
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